(But if you are a man, it is very unlikely you suffer from it, it is an extreme rare condition in men).
an elderly man undergoing treatment with TACE (chlorotrianisene), an estrogen drug used to treat prostate cancer. The patient had been taking TACE for over 10 years for an adenocarcinoma of the prostate, when doctors found that he also had an endometrioma (mass of endometrial uterine tissue) of the lower abdominal wall. In the report, doctors denied the possibility of any remnant uterine tissue, but a postmortem exam/autopsy was never performed to confirm their theory.(Excerpted from ).
|Source: https://es.pinterest.com/fredyeomans/endometriosis/. I would like to credit the author!. I don't quite agree with that endometriosis can't be prevented, because I think the situation is quite more complex than a simple yer or not, but in general it is a great chart.|
Other than that there have only been six other cases of male endometriosis reported in locations such as the(Excerpted from , and . However, if we look at all of these cases, most of them have one thing in common; they have been undergoing long term estrogen therapy for the treatment of prostate cancer. This is quite important, as unusual presentations of a disease can often give us clues as to how it arises in women. ).
You may think that the endo condition has only been found in elderly men undergoing hormone therapy for some reason, but there has been at least one report of endo in a young and healthy men:
One of theof male endometriosis was from a young man aged 27 who was otherwise completely healthy, very different to the other reports which are mostly much older men with prostate cancer. So not only was this an unusual presentation of endometriosis, it was an unusual, unusual presentation, if that makes sense. So what can this tell us about the disease as a whole? (Excerpted from
Of course, next question is ).
- What causes endometriosis in men?. Docs have advanced their hypotheses:
The authors of this report looked to the very beginning of the development of the reproductive organs. Whilst still only a developing embryo, there are different structures that will form the male and female reproductive systems (there’s a nice illustration here). The female organs develop from the müllerian duct which in male embryos regresses because the embryo produces the imaginatively named müllerian inhibiting substance (MIS). The authors of this report suggest that exposure to certain environmental toxicants (such as diethylstilbestrol or other hormone disrupters) whilst the embryo is still developing, may lead to abnormal production of MIS which in turn stops the müllerian duct regressing properly, leaving small remnant patches of tissue that could, given the right stimulus, develop into endometrial like tissue, which would appear as endometriosis.(Excerpted from ).
To my understanding these arguments, while giving a (at least to an extent) convicing reason to why a man can develope endo, fail totally to explain when, where and to what extent does this condition develop.
Where can it grow is a key question. Do these cells remain undifferentiate in the tissues until some condition make them start acting as uterus shedding?. Can they migrate form one part of the body to another? (there are women suffering form endometrial cyst in the skin).
Understanding these factors could lead to significatively more effective health advices to the millions of women suffering from this condition. The lesson given we have to take from the plain fact that there are men affected by endo is that this disease needs a more indeep understanding to this serious illness that affects to an attonishing proportion of almost 10% of women.
Here there are some links to studies on endometriosis in men: